Takuji Suzuki Selected Research

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)

1/2022	A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption.
1/2020	Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis.
1/2019	Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra-/- Mice.
1/2018	Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.
1/2018	Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis.
12/2017	Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency.
1/2017	Targeting cholesterol homeostasis in lung diseases.
1/2016	Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.
11/2014	A standardized blood test for the routine clinical diagnosis of impaired GM-CSF signaling using flow cytometry.
10/2014	Pulmonary macrophage transplantation therapy.

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Takuji Suzuki Research Topics

Disease

22	Pulmonary Alveolar Proteinosis 01/2022 - 04/2008
16	Neoplasms (Cancer) 06/2022 - 07/2002
9	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 03/2009
8	Infections 06/2022 - 10/2009
8	Inflammation (Inflammations) 05/2022 - 03/2003
7	Lung Diseases (Lung Disease) 01/2022 - 10/2014
6	COVID-19 07/2022 - 01/2021
5	Lung Neoplasms (Lung Cancer) 07/2022 - 05/2008
5	Pneumonia (Pneumonitis) 07/2022 - 08/2008
5	Leukemia 06/2008 - 01/2005
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 07/2006
3	Hypoxia (Hypoxemia) 05/2022 - 06/2008
3	Obesity 09/2016 - 10/2011
3	Autoimmune Diseases (Autoimmune Disease) 11/2014 - 03/2009
2	Pulmonary Hypertension 06/2022 - 04/2022
2	Sarcoidosis (Schaumann Disease) 01/2022 - 03/2021
2	Lung Injury 01/2022 - 12/2021
2	Disease Progression 01/2022 - 01/2019
2	Colorectal Neoplasms (Colorectal Cancer) 04/2021 - 08/2008
2	Lymphadenopathy 03/2021 - 03/2020
2	Carcinoma (Carcinomatosis) 10/2011 - 01/2005
2	Fibrosis (Cirrhosis) 10/2011 - 02/2007
2	Hepatitis 02/2007 - 10/2005
2	Melanoma (Melanoma, Malignant) 04/2006 - 01/2005
1	Post-Acute COVID-19 Syndrome 09/2022
1	Acquired Immunodeficiency Syndrome (AIDS) 07/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2022
1	Chronic Renal Insufficiency 07/2022
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 06/2022
1	Pulmonary Edema 06/2022
1	Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary) 06/2022
1	Dyspnea (Shortness of Breath) 06/2022
1	Cellulitis 05/2022
1	Fever (Fevers) 05/2022
1	Pulmonary Arterial Hypertension 05/2022
1	Pleural Effusion (Pleural Effusions) 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2022

Drug/Important Bio-Agent (IBA)

21	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2022 - 04/2008
13	Surface-Active Agents (Surfactants)IBA 01/2022 - 08/2008
8	TeaIBA 06/2020 - 02/2005
7	Granulocyte-Macrophage Colony-Stimulating Factor Receptors (GM-CSF Receptor)IBA 01/2022 - 04/2008
6	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2005
6	AutoantibodiesIBA 01/2014 - 03/2009
4	LipopolysaccharidesIBA 01/2022 - 03/2003
4	Catechin (Z 7300)IBA 06/2020 - 10/2005
4	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2019 - 03/2009
4	Calcitriol (Calcijex)FDA LinkGeneric 06/2008 - 01/2005
3	Fluvoxamine (Luvox)FDA LinkGeneric 09/2022 - 01/2022
3	Pharmaceutical PreparationsIBA 02/2022 - 01/2022
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2014
3	LipidsIBA 01/2020 - 07/2010
3	Secretory Leukocyte Peptidase InhibitorIBA 04/2014 - 03/2003
3	DNA (Deoxyribonucleic Acid)IBA 06/2008 - 06/2006
3	CytokinesIBA 10/2005 - 07/2002
2	Antiviral Agents (Antivirals)IBA 05/2022 - 01/2021
2	InterleukinsIBA 01/2022 - 01/2005
2	Epidermal Growth Factor (EGF)IBA 01/2022 - 08/2008
2	SteroidsIBA 01/2022 - 01/2021
2	Interleukin-8 (Interleukin 8)IBA 01/2022 - 01/2005
2	Small Interfering RNA (siRNA)IBA 12/2021 - 04/2014
2	Transcription Factors (Transcription Factor)IBA 06/2015 - 06/2008
2	Urethane (Ethyl Carbamate)IBA 04/2014 - 05/2008
2	Messenger RNA (mRNA)IBA 07/2010 - 07/2002
2	ErbB Receptors (EGF Receptor)IBA 08/2008 - 07/2006
2	Gefitinib (Iressa)FDA Link 08/2008 - 07/2006
2	Karyopherins (Importin)IBA 06/2008 - 04/2006
2	Interleukin-3 (Interleukin 3)IBA 04/2008 - 04/2008
2	GalactosamineIBA 02/2007 - 10/2005
2	Cholecalciferol (Vitamin D3)FDA Link 04/2006 - 01/2005
2	Chemokine CX3CL1IBA 04/2006 - 05/2005
1	Sigma-1 ReceptorIBA 09/2022
1	sotrovimabIBA 07/2022
1	remdesivirIBA 07/2022
1	Vasodilator Agents (Vasodilators)IBA 06/2022
1	DiureticsIBA 06/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2022
1	Immune Checkpoint InhibitorsIBA 06/2022
1	B7-H1 AntigenIBA 06/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 05/2022
1	Analgesics (Analgesic Drugs)IBA 05/2022
1	chrysinIBA 05/2022
1	Semaxinib (SU5416)IBA 05/2022
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 05/2022
1	AcidsIBA 01/2022
1	Gemcitabine FDA Link 01/2022
1	130-nm albumin-bound paclitaxelIBA 01/2022
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2022

Therapy/Procedure

6	Transplantation 06/2022 - 10/2014
6	Therapeutics 01/2022 - 05/2005
4	Drug Therapy (Chemotherapy) 04/2021 - 07/2006
3	Immunotherapy 04/2006 - 05/2004
2	Aftercare (After-Treatment) 01/2022 - 05/2005
1	Renal Dialysis (Hemodialysis) 07/2022
1	Hematopoietic Stem Cell Transplantation 06/2022
1	Personal Protective Equipment 06/2022
1	Endarterectomy (Thromboendarterectomy) 04/2022
1	Hydrotherapy (Whirlpool Bath) 01/2022
1	Pneumonectomy (Lung Volume Reduction) 01/2022